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Home / Hospitals / South Carolina

Best Hospitals in South Carolina, Graded A–F

All 52 graded Medicare-certified hospitals in South Carolina, scored from CMS Care Compare — overall rating, mortality, safety of care and readmissions — against South Carolina hospitals of the same type. Grades are computed, never edited, and every input is shown on the hospital page.

CMS data as of Sep 2026 · graded Sep 11, 2026
Grade distribution — South Carolina
A3
B16
C18
D10
F5
Highest graded
APrisma Health Greenville Mem...A
Greenville · CMS overall rating 4 of 5 — above median...See grade
52 hospitalsgraded in South Carolina · 3 earned an A
All South Carolina Charleston (5)Columbia (5)Greenville (3)Florence (2)Mount Pleasant (2)Spartanburg (2)Aiken (1)Anderson (1)Beaufort (1)
Highest in South Carolina 1

Prisma Health Greenville Memorial Hospital - Greenville, SC · Acute care hospital · voluntary non-profit - private CMS Care Compare · data as of Sep 2026

  • CMS overall rating 4 of 5 — above median among South Carolina acute care hospitals
  • Mortality: 2 measures better than the national rate, 0 worse, of 8
  • Safety: 4 measures better than the national rate, 0 worse, of 7
AScore 80 · ExcellentSee Full Grade
(864) 455-7000 Greenville, GREENVILLE County Birthing-Friendly
2

St Francis-Downtown - Greenville, SC · Acute care hospital · voluntary non-profit - private CMS Care Compare · data as of Sep 2026

  • CMS overall rating 4 of 5 — above median among South Carolina acute care hospitals
  • Mortality: 1 measure better than the national rate, 0 worse, of 8
  • Safety: 2 measures better than the national rate, 0 worse, of 8
AScore 75 · ExcellentSee Full Grade
(800) 805-5678 Greenville, GREENVILLE County Emergency dept. Birthing-Friendly
3

Prisma Health Greer Memorial Hospital - Spartanburg, SC · Acute care hospital · voluntary non-profit - private CMS Care Compare · data as of Sep 2026

  • CMS overall rating 5 of 5 — top 10% among South Carolina acute care hospitals
  • Mortality: 0 measures better than the national rate, 0 worse, of 5
  • Safety: 1 measure better than the national rate, 0 worse, of 6
AScore 74 · ExcellentSee Full Grade
(864) 848-8200 Spartanburg, SPARTANBURG County Emergency dept. Birthing-Friendly
4

Prisma Health Baptist - Columbia, SC · Acute care hospital · voluntary non-profit - private CMS Care Compare · data as of Sep 2026

  • CMS overall rating 4 of 5 — above median among South Carolina acute care hospitals
  • Mortality: 0 measures better than the national rate, 0 worse, of 6
  • Safety: 1 measure better than the national rate, 0 worse, of 8
BScore 68 · GoodSee Full Grade
(803) 296-5678 Columbia, RICHLAND County Emergency dept. Birthing-Friendly
5

Prisma Health Laurens County Hospital - Clinton, SC · Acute care hospital · voluntary non-profit - private CMS Care Compare · data as of Sep 2026

  • CMS overall rating 4 of 5 — above median among South Carolina acute care hospitals
  • Mortality: 0 measures better than the national rate, 0 worse, of 5
  • Safety: 1 measure better than the national rate, 0 worse, of 2
BScore 68 · GoodSee Full Grade
(864) 833-9100 Clinton, LAURENS County Emergency dept.
6

Roper Hospital - Charleston, SC · Acute care hospital · voluntary non-profit - private CMS Care Compare · data as of Sep 2026

  • CMS overall rating 4 of 5 — above median among South Carolina acute care hospitals
  • Mortality: 1 measure better than the national rate, 0 worse, of 8
  • Safety: 4 measures better than the national rate, 0 worse, of 8
BScore 67 · GoodSee Full Grade
(843) 724-2800 Charleston, CHARLESTON County Emergency dept.
7

Columbia Sc Va Medical Center - Columbia, SC · Acute care hospital · veterans health administration CMS Care Compare · data as of Sep 2026

  • CMS overall rating 5 of 5 — top 10% among South Carolina acute care hospitals
  • Mortality: 0 measures better than the national rate, 0 worse, of 3
  • Safety: 0 measures better than the national rate, 0 worse, of 3
BScore 64 · GoodSee Full Grade
(803) 695-7980 Columbia, RICHLAND County Emergency dept.
8

Prisma Health Patewood Hospital - Greenville, SC · Acute care hospital · voluntary non-profit - private CMS Care Compare · data as of Sep 2026

  • CMS overall rating 5 of 5 — top 10% among South Carolina acute care hospitals
  • Mortality: 0 measures better than the national rate, 0 worse, of 1
  • Safety: 0 measures better than the national rate, 0 worse, of 3
BScore 64 · GoodSee Full Grade
(864) 797-1000 Greenville, GREENVILLE County Birthing-Friendly
9

Self Regional Healthcare - Greenwood, SC · Acute care hospital · voluntary non-profit - private CMS Care Compare · data as of Sep 2026

  • CMS overall rating 4 of 5 — above median among South Carolina acute care hospitals
  • Mortality: 0 measures better than the national rate, 0 worse, of 8
  • Safety: 4 measures better than the national rate, 0 worse, of 7
BScore 62 · GoodSee Full Grade
(864) 227-4111 Greenwood, GREENWOOD County Emergency dept. Birthing-Friendly
10

Prisma Health Richland Hospital - Columbia, SC · Acute care hospital · voluntary non-profit - private CMS Care Compare · data as of Sep 2026

  • CMS overall rating 3 of 5 — below median among South Carolina acute care hospitals
  • Mortality: 1 measure better than the national rate, 0 worse, of 8
  • Safety: 3 measures better than the national rate, 0 worse, of 7
BScore 61 · GoodSee Full Grade
(803) 296-2548 Columbia, RICHLAND County Emergency dept. Birthing-Friendly
11

Coastal Carolina Hospital - Hardeeville, SC · Acute care hospital · proprietary CMS Care Compare · data as of Sep 2026

  • CMS overall rating 4 of 5 — above median among South Carolina acute care hospitals
  • Mortality: 0 measures better than the national rate, 0 worse, of 5
  • Safety: 0 measures better than the national rate, 0 worse, of 3
BScore 61 · GoodSee Full Grade
(843) 784-8000 Hardeeville, JASPER County Emergency dept. Birthing-Friendly
12

Prisma Health Baptist Parkridge - Columbia, SC · Acute care hospital · voluntary non-profit - private CMS Care Compare · data as of Sep 2026

  • CMS overall rating 4 of 5 — above median among South Carolina acute care hospitals
  • Mortality: 0 measures better than the national rate, 0 worse, of 4
  • Safety: 0 measures better than the national rate, 0 worse, of 4
BScore 61 · GoodSee Full Grade
(803) 907-7011 Columbia, LEXINGTON County Emergency dept. Birthing-Friendly
13

Beaufort County Memorial Hospital - Beaufort, SC · Acute care hospital · government - local CMS Care Compare · data as of Sep 2026

  • CMS overall rating 4 of 5 — above median among South Carolina acute care hospitals
  • Mortality: 0 measures better than the national rate, 0 worse, of 7
  • Safety: 1 measure better than the national rate, 0 worse, of 7
BScore 61 · GoodSee Full Grade
(843) 522-5200 Beaufort, BEAUFORT County Emergency dept. Birthing-Friendly
14

Charleston Va Medical Center - Charleston, SC · Acute care hospital · veterans health administration CMS Care Compare · data as of Sep 2026

  • CMS overall rating 5 of 5 — top 10% among South Carolina acute care hospitals
  • Mortality: 2 measures better than the national rate, 0 worse, of 5
  • Safety: 0 measures better than the national rate, 0 worse, of 4
BScore 60 · GoodSee Full Grade
(843) 577-5011 Charleston, CHARLESTON County Emergency dept.
15

Anmed Health - Anderson, SC · Acute care hospital · voluntary non-profit - private CMS Care Compare · data as of Sep 2026

  • CMS overall rating 4 of 5 — above median among South Carolina acute care hospitals
  • Mortality: 0 measures better than the national rate, 1 worse, of 8
  • Safety: 4 measures better than the national rate, 0 worse, of 7
BScore 59 · GoodSee Full Grade
(864) 512-2830 Anderson, ANDERSON County Emergency dept. Birthing-Friendly
16

Novant Health East Cooper Medical Center - Mount Pleasant, SC · Acute care hospital · proprietary CMS Care Compare · data as of Sep 2026

  • CMS overall rating 4 of 5 — above median among South Carolina acute care hospitals
  • Mortality: 0 measures better than the national rate, 0 worse, of 4
  • Safety: 0 measures better than the national rate, 0 worse, of 3
BScore 58 · GoodSee Full Grade
(843) 881-0100 Mount Pleasant, CHARLESTON County Emergency dept. Birthing-Friendly
17

Prisma Health Baptist Easley Hospital - Easley, SC · Acute care hospital · voluntary non-profit - private CMS Care Compare · data as of Sep 2026

  • CMS overall rating 4 of 5 — above median among South Carolina acute care hospitals
  • Mortality: 0 measures better than the national rate, 0 worse, of 6
  • Safety: 0 measures better than the national rate, 0 worse, of 6
BScore 58 · GoodSee Full Grade
(864) 442-7606 Easley, PICKENS County Emergency dept.
18

Prisma Health Hillcrest Hospital - Simpsonville, SC · Acute care hospital · voluntary non-profit - private CMS Care Compare · data as of Sep 2026

  • CMS overall rating 4 of 5 — above median among South Carolina acute care hospitals
  • Mortality: 0 measures better than the national rate, 0 worse, of 5
  • Safety: 0 measures better than the national rate, 0 worse, of 3
BScore 58 · GoodSee Full Grade
(864) 454-6100 Simpsonville, GREENVILLE County Emergency dept.
19

Tidelands Waccamaw Community Hospital - Murrells Inlet, SC · Acute care hospital · voluntary non-profit - private CMS Care Compare · data as of Sep 2026

  • CMS overall rating 4 of 5 — above median among South Carolina acute care hospitals
  • Mortality: 0 measures better than the national rate, 0 worse, of 7
  • Safety: 0 measures better than the national rate, 0 worse, of 5
BScore 58 · GoodSee Full Grade
(843) 652-1000 Murrells Inlet, HORRY County Emergency dept. Birthing-Friendly
20

Pelham Medical Center - Greer, SC · Acute care hospital · government - hospital district or authority CMS Care Compare · data as of Sep 2026

  • CMS overall rating 5 of 5 — top 10% among South Carolina acute care hospitals
  • Mortality: 0 measures better than the national rate, 0 worse, of 5
  • Safety: 0 measures better than the national rate, 0 worse, of 4
CScore 58 · AverageSee Full Grade
(864) 560-6554 Greer, GREENVILLE County Emergency dept.
21

Roper St Francis Hospital-Berkeley Inc - Summerville, SC · Acute care hospital · voluntary non-profit - private CMS Care Compare · data as of Sep 2026

  • CMS overall rating 5 of 5 — top 10% among South Carolina acute care hospitals
  • Mortality: 0 measures better than the national rate, 0 worse, of 5
  • Safety: 0 measures better than the national rate, 0 worse, of 3
CScore 58 · AverageSee Full Grade
(854) 529-3002 Summerville, DORCHESTER County Emergency dept. Birthing-Friendly
22

Musc Health Lancaster Medical Center - Lancaster, SC · Acute care hospital · proprietary CMS Care Compare · data as of Sep 2026

  • CMS overall rating 4 of 5 — above median among South Carolina acute care hospitals
  • Mortality: 0 measures better than the national rate, 0 worse, of 7
  • Safety: 1 measure better than the national rate, 0 worse, of 5
CScore 54 · AverageSee Full Grade
(803) 286-1481 Lancaster, LANCASTER County Emergency dept. Birthing-Friendly
23

Prisma Health Oconee Memorial Hospital - Seneca, SC · Acute care hospital · voluntary non-profit - private CMS Care Compare · data as of Sep 2026

  • CMS overall rating 4 of 5 — above median among South Carolina acute care hospitals
  • Mortality: 0 measures better than the national rate, 0 worse, of 7
  • Safety: 1 measure better than the national rate, 0 worse, of 7
CScore 54 · AverageSee Full Grade
(864) 482-3100 Seneca, OCONEE County Emergency dept. Birthing-Friendly
24

Musc Health Columbia Medical Center Downtown - Columbia, SC · Acute care hospital · voluntary non-profit - private CMS Care Compare · data as of Sep 2026

  • CMS overall rating 3 of 5 — below median among South Carolina acute care hospitals
  • Mortality: 0 measures better than the national rate, 0 worse, of 8
  • Safety: 1 measure better than the national rate, 0 worse, of 7
CScore 53 · AverageSee Full Grade
(803) 256-5300 Columbia, RICHLAND County Emergency dept.
25

Musc Health Florence Medical Center - Florence, SC · Acute care hospital · government - state CMS Care Compare · data as of Sep 2026

  • CMS overall rating 3 of 5 — below median among South Carolina acute care hospitals
  • Mortality: 0 measures better than the national rate, 0 worse, of 7
  • Safety: 1 measure better than the national rate, 0 worse, of 6
CScore 53 · AverageSee Full Grade
(843) 674-2500 Florence, FLORENCE County Emergency dept. Birthing-Friendly
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South Carolina hospitals by city

How we grade hospitals

What data goes into a grade?
CMS Care Compare Hospital General Information: CMS overall rating (25), Mortality (25), Safety of care (25), Readmission (25). Each metric is percentile-ranked against South Carolina hospitals of the same type; A ≥ 72, B ≥ 58, C ≥ 42, D ≥ 28, F below. Hospitals with fewer than three of the four metrics are shown as "Not graded".
Why is a well-known hospital graded C?
The grade measures outcomes CMS reports — death rates, complications, infections, readmissions — not reputation, research or specialist rankings. A large teaching hospital that treats the sickest patients can score average on these measures. Use the grade as one input, alongside the specialists you need.
Can a hospital pay to improve its grade?
No. Grades are computed from public data and have no editable field. Nothing on this page is sponsored.